CLAUDIO SOTO, PhD

CSO and CoFounder

“Science is powerful. I want to change the world through science.”

In addition to his role as CSO at Amprion, Dr. Soto also serves as professor of neurology at McGovern Medical School at UTHealth in Houston. He is director of the George and Cynthia Mitchell Center for Alzheimer’s Disease and related Brain Disorders at the University of Texas Medical School. After receiving his PhD from the University of Chile and performing postdocs at the Catholic University of Chile and at the New York University School of Medicine, Mr. Soto became an assistant professor in 1995.

Dr. Soto participated in the creation of the New York-based biotech company, Axonyx Inc, which traded in Nasdaq in 1997 at a peak valuation of over $300 million. Between 1999 and 2003, Dr. Soto was Senior Scientist, Chairman of the Department of Molecular Neurobiology and Senior Executive Scientific Advisor for Neurology at Serono International in Switzerland. He was responsible for the Neurology portfolio and successfully took his own discovery to human clinical trials in the field of Alzheimer’s disease.

Between 2003 and 2008, he served as Director of the George and Cynthia Mitchell Center for Neurodegenerative Diseases and Professor on the Departments of Neurology, Neuroscience & Cell Biology and Biochemistry & Molecular Biology at the University of Texas Medical Branch in Galveston.

For the past 20 years, he and his colleagues have engaged in the research of molecular basis for neurodegenerative diseases associated with misfolded proteins and brain accumulation of these misfolded proteins, particularly focusing in Alzheimer’s and prion-related disorders. His work has led to the development of novel strategies for treatment and diagnosis of these diseases.

Dr. Soto has published over 150 peer reviewed scientific publications, including Cell, Nature, Science, Nature medicine, The Lancet, The New England Journal of Medicine, PNAS, Neuron, EMBO J, and etc. Dr. Soto has received numerous awards and often serves as speaker in many scientific conventions worldwide. Dr. Soto has been awarded many grants from NIH, and private foundations for a total funding of over US$30 million.

Dr. Soto’s discoveries have been extensively featured in scientific literature, newspapers, magazines, as well as interviews on television and radio shows worldwide.