BrainStorm Live Episode 16: How to Interpret A Negative Result From Amprion’s Early Testing?
Amprion’s CEO Dr. Russ Lebovitz discusses how to interpret the negative result in Amprion’s Early Detection Testing℠ for Alzheimer’s and Parkinson’s. The absence of Prions suggests that the patient does not have an actively progressing neurodegenerative disease, while other causes can be investigated further.
Negative Results from Early Testing for Alzheimer’s & Parkinson’s
So in patients that have no evidence of soluble misfolded aggregates of Abeta, Tau or Synuclein, we believe that that indicates that they are not undergoing a progressive neurodegenerative disease and that to get to levels, even if it started the next day, to be toxic could be five to twenty years or more so we believe that there’s no evidence of soluble misfolded Abeta, Synuclein or Tau that most likely these patients are not on any path towards Alzheimer’s, Parkinson’s, what we call Tauopathy neurodegenerative diseases and in the case that we talked about when patients show up with the first early signs that might be Dementia or might be a motor neurodegenerative problem, the absence of any soluble misfolded proteins of Abeta, Synuclein or Tau, would indicate that this patient probably is not suffering from a progressive neurodegenerative disease and it makes sense to either look elsewhere or to consider that this might just be part of normal aging and not likely to progress rapidly.
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